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Home > Reception: COVID Vaccine query

Reception: COVID Vaccine query

Use of the Pfizer-BioNTech covid-19 vaccine in people with a history of severe allergies was temporarily stopped in the UK after two healthcare workers experienced anaphylactic reactions in early December. The Medicines and Healthcare Products Regulatory Agency (MHRA) stated that “any person with a history of anaphylaxis to a vaccine, medicine, or food should not receive the Pfizer/BioNTech vaccine.” However, MHRA revised its position on 30 December after careful consideration based on enhanced surveillance of over one million doses of the vaccine in the UK and North America—including in jurisdictions where people with serious allergies were never barred from receiving the vaccine. It found no evidence of an increased risk of anaphylaxis to the Pfizer-BioNTech vaccine among people with serious but unrelated allergy histories and advised that only people who had an allergic reaction to the first dose of this vaccine, or who previously had reactions to any of its components, should not receive it.

Pfizer vaccine ingredients

The COVID-19 vaccine does not contain any animal products or egg.

  • The active substance is BNT162b2 RNA.
  • Polyethylene glycol/macrogol (PEG) as part of ALC-0159
  • ALC-0315 = (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
  • ALC-0159 = 2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, -
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine,
  • 5 - cholesterol
  • potassium chloride
  • potassium dihydrogen phosphate
  • sodium chloride
  • disodium hydrogen phosphate dihydrate
  • sucrose

Oxford AstraZeneca vaccine ingredients

One dose (0.5 ml) contains: COVID 19 Vaccine (ChAdOx1-S* recombinant) 5 × 10^10 viral particles

*Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS CoV 2 Spike glycoprotein. Produced in genetically modified human embryonic kidney (HEK) 293 cells.

This product contains genetically modified organisms (GMOs).

The other excipients are:

  • L-histidine
  • L-histidine hydrochloride monohydrate
  • magnesium chloride hexahydrate
  • polysorbate 80
  • ethanol
  • sucrose
  • sodium chloride
  • disodium edetate dihydrate
  • water for injections
What is an anaphylactoid reaction?
If you are having chemotherapy?

Covid vaccines are not 'live' vaccines. They can be given before, during or after cancer treatment. It is possible that the vaccines may be slightly less effective for people having chemotherapy or other cancer treatments.

If you have any queries regarding having the vaccine and it has not been answered by the information above please complete the form below where your request will be sent to the GP to review. 

Please do not write any clinical queries on this form. Any clinical queries or request for appointments via this form will be discarded. To make an appointment either book online via the NHS app/Patient access or by calling reception 01926 316711. We will start to process your form by the next working day but it will take up to 2 working days to complete. Please do not call before 2 working days as you will not receive a status update from reception or the administrative team. If you are not a registered patient then your form will be discarded. This service is only for patients registered at the surgery aged 16 and over; and for parents or legal guardians of children. Forms must be completed in the UK due to GDPR regulations.

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Reception: COVID Vaccine query
Ensure you give plenty of detail including when, the allergen and what treatment you needed to resolve the reaction.

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